The William sisters are two-time champions at the U.S Open and will pair for the first time since 2018 Roland Garros.
Due to reciprocal wild card deals with Tennis Australia and the French Tennis Federation, Venus and Sofia will be joined by fellow Americans CoCo Vandeweghe, Elizabeth Mandlik, Peyton Stearns, Eleana Yu, Australia's Jaimee Fourlis, and France's Harmony Tan.
while Venus pulled out due to an injury, Kenin announced her withdrawal, as the 22-year-old American has tested positive for Covid-19
Serena, No. 1 seed, defeated Venus 3-6, 6-3, 6-4 in a thrilling match that lasted for two hours and 19 minutes on Thursday played at the Centre Court.
Then, the Romanian had the edge as she seized the first opportunity she had to break Venus' serve for a 3-2 lead.
Williams also dropped a set and had to work hard to get past Cornet with a scoreline of 6-3, 4-6, 6-0.
The come-from-behind victory came a day after she eliminated top seed and world number three Caroline Wozniacki.
Of 15 Americans in the top 100 of the WTA year-end rankings in 1999, four women were African-American. Serena won the U.S. Open that year.
Six-time champion Serena eased into Friday's third round encounter against her sister with a 6-2 6-2 win