— Tottenham Hotspur (@SpursOfficial) March 7, 2018
Spurs are trotting out in a 4-2-3-1 formation, as expected, with goalkeeper and captain Hugo Lloris leading the side from the back.
Kieran Tripper, Davinson Sanchez, Jan Vertonghen and Ben Davies complete their four-man defence while Eric Dier partners Mousa Dembele in central midfield.
Dele Alli, Heung-Min Son and Christian Eriksen line up behind star striker Harry Kane.
Juventus XI: Buffon; Barzagli, Benatia, Chiellini, Alex Sandro; Khedira, Pjanic, Matuidi; Dybala, Higuain, Douglas Costa
— JuventusFC (@juventusfcen) March 7, 2018
The visitors are lining up in a 4-3-3, with Gonzalo Higuain starting as the centre-forward, flanked by Douglas Costa and Paulo Dybala.
Sami Khedira, Miralem Pjanic and Blaise Matuidi feature in the middle while Alex Sandro, Chiellini, Benatia and Barzagli appear in a four-man defence ahead of skipper and custodian Gianluigi Buffon.
The tie is evenly poised after the first leg in Turin ended in a 2-2 draw but the fact that Spurs scored two away goals gives them a slight edge over the Bianconeri.
However, they will be wary of complacency as a sluggish start in the first leg, which saw them go 2-0 down with little over 10 minutes played, nearly cost them the tie in Italy and a repeat performance will be disastrous against the in-form Italian outfit.
Tottenham Hotspur: Lloris (c), Trippier, Sanchez, Vertonghen, Davies, Dier, Dembele, Eriksen, Dele, Son and Kane.
Juventus: Buffon (c), Sandro, Chiellini, Benatia, Barzagli, Pjanic, Khedira, Matuidi, Costa, Higuain and Dybala.
Match kicks-off at 20.45 GMT/01.15 IST.