The Centre for Augmenting WAR with COVID-19 Health Crisis (CAWACH), an initiative by the Department of Science and Technology (DST), has selected Bangalore based startup Acculi Labs to develop a COVID risk assessment profile called Lyfas COVID score.

Acculi Labs is armed with ‘Lyfas’ a clinical-grade, non-invasive, digital functional biomarker smartphone tool for screening, early detection, root cause analysis, acute event risk assessment, prognosis, and home monitoring of chronic diseases which they have repurposed to Lyfas COVID score.

The new technology, developed with support from the DST, will detect the possible infection in an asymptomatic individual to prioritise the conventional testing queue as well as carry out a risk assessment of an asymptomatic individual to become symptomatic and risk assessment of an asymptomatic individual for recovery.

Acculi Labs was selected after several rounds of screening for a solution towards mass screening. Its product Lyfas has received a grant of Rs 30 Lakh from DST and is now virtually supported by IIT Madras, Healthcare Technology Innovation Centre (HTIC), MedTech Incubator.

Lyfas is an Android application in which, when one keeps the index finger on the rear phone camera of a mobile phone for 5 minutes, captures the capillary pulse and blood volume change and derive 95 biomarkers with proprietary algorithms and signal processing techniques.

It uses the power of smartphone processor and smartphone sensors to capture a bunch of body signals. The signals are subsequently processed on the principle of Photoplethysmography (PPG), Photo Chromatography (PCG), Arterial Photoplethysmography (APPG), mobile spirometry, and Pulse Rate Variability(PRV).

Lyfas then provides cardio-respiratory, cardio-vascular, hematology, hemorheology, neurology based parameters that are capable of tracking minute pathophysiological changes in the body. These changes are further profiled into organ system-wide response.

The technology is focused on population screening, monitoring of quarantined individuals, and surveillance at the community spreading phase. It has been proved to detect asymptomatic individuals with an accuracy of 92%, specificity of 90%, and a sensitivity of 92% in a study conducted with Medanta Medicity hospital.

Witnessing the success of the study, Medanta ethics committee has approved it for a larger population study. This study is currently registered in Clinical Trials Registry- India (CTRI) and is acknowledged by World Health Organisation (WHO). While AarogyaSetu works on contact tracing where one has to enter your symptoms, Lyfas is a proper medical screening test which purely depends upon test results.