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Mother’s milk may boost the immunity of a newborn in such a way that it may work against certain diseases like tuberculosis TB just as vaccination does suggests new research.
quot;Some vaccines are not safe to give a newborn baby and others just don’t work very well in newbornsquot; said lead researcher Ameae Walker Professor at the University of California Riverside School of Medicine in the US.
quot;If we can instead vaccinate mom or boost her vaccination shortly before she becomes pregnant transferred immune cells during breastfeeding will ensure that the baby is protected early onquot; Walker explained.
Scientists have long understood that mother’s milk provides immune protection against some infectious agents through the transfer of antibodies a process referred to as quot;passive immunity.quot;
The new research published in the Journal of Immunology showed that mother’s milk also contributes to the development of the baby’s own immune system by a process the team calls quot;maternal educational immunity.quot;
Specific maternal immune cells in the milk cross the wall of the baby’s intestine to enter an immune organ called the thymus. Once there they quot;educatequot; developing cells to attack the same infectious organisms to which the mother has been exposed.
quot;While our work has used mouse models because we can study the process in detail this way we do know that milk cells cross into human babies as wellquot; Walker pointed out.
The researchers showed that you can vaccinate the mother and this results in vaccination of the baby through this process.
One of the infectious agents the research team studied was the organism that causes tuberculosis. Generally babies directly vaccinated against TB do not have a very good response.
quot;We hope that by vaccinating the mother who will eventually nurse the baby we will improve infant immunity against TBquot; Walker said.
quot;It’s like vaccinating the baby without actually vaccinating the baby. In some instances our work has shown that immunity against TB is far more effective if acquired through the milk than if acquired through direct vaccination of the babyquot; Walker noted.
quot;Of course clinical trials will need to be conducted to test whether this is the case in humansquot; Walker said.