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Tag: gene conversion

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  • Breakage and exchange

    Breakage and exchange

    The homologous recombination is based on DNA breakage-and-exchange but it does not in itself provide much information concerning the underlying molecular mechanisms. One of the simplest breakage-and-exchange models that might be envisioned would involve the cleavage of two homologous, double-stranded DNA molecules at comparable locations, followed by exchange and rejoining of the cut ends. This …

    January 11, 2017